| Paperino e le notti di luna piena | 2000 | Sergio Tulipano, Sandro Dossi | Story | 30 | Italy | 16 |
| Zio Paperone e la luna a specchio | 2000 | Fabio Michelini, Luciano Gatto | Story | 33 | Italy | 16 |
| Paperino & Ciccio e il terrier yetico | 2000 | Alberto Savini, Luciano Milano | Story | 18 | Italy | 16 |
| Who's The Bank Robber? | 2000 | Lars Jensen, Tino Santanach Hernandez | Story | 1 | Denmark | 15 |
| Bons baisers du Mayöland | 2000 | Gilles Corre | Story | 8 | France | 15 |
| Nieuwe computer | 2000 | Pascal Oost, Carry Brugman | Story | 1 | Holland | 15 |
| als wethouder | 2000 | Jan Kruse, Bas Heymans | Story | 10 | Holland | 15 |
| Zeemeermin | 2000 | Wilma van den Bosch | Story | 1 | Holland | 15 |
| I paperi della valle solitaria | 2000 | Gianfranco Cordara, Marco Gervasio | Story | 25 | Italy | 15 |
| Rockerduck sindaco antipaperone | 2000 | Bruno Concina, Lara Molinari | Story | 30 | Italy | 15 |
| Untitled article | 2000 | | Article | 1 | Brazil | 14 |
| Untitled cover | 2000 | Josep Tello Gonzalez | Cover | 1 | Denmark | 14 |
| It's Only Duck 'N' Roll | 2000 | Darko Macan, Xavier Vives Mateu | Story | 33 | Denmark | 14 |
| Bioscoopkaartjes | 2000 | Nino Russo, Comicup Studio | Story | 1 | Holland | 14 |
| Jaap Kadet | 2000 | Frank Jonker, Bas Heymans | Story | 4 | Holland | 14 |
| Paperino e la caccia al veglione | 2000 | Rudy Salvagnini, Alessandro Barbucci | Story | 5 | Italy | 14 |
| Paperino e il glorioso cimelio | 2000 | Marco Bosco, Giorgio Di Vita | Story | 21 | Italy | 14 |
| Paperoga e il peso... del presente | 2000 | Alberto Savini, Andrea Ferraris | Story | 15 | Italy | 14 |
| Captains Outrageous | 2000 | Bob Langhans, José Maria Manrique | Story | 35 | Denmark | 13 |
| Go West, Young Duck! | 2000 | Spectrum Associates, Miguel Fernández Martinez | Story | 56 | Denmark | 13 |
| Brain Drain | 2000 | Spectrum Associates, Miguel Fernández Martinez | Story | 50 | Denmark | 13 |
| Paperinik e il doppio impegno | 2000 | Carlo Panaro, Carlo Limido | Story | 30 | Italy | 13 |
| Paperino e il caos metropolitano | 2000 | Emanuela Negrin, Lucio Leoni | Story | 30 | Italy | 13 |
| Paperino e la casa alla moda | 2000 | Blasco Pisapia | Story | 30 | Italy | 13 |
| A Way With Women | 2000 | Paul Halas, Tino Santanach Hernandez | Story | 16 | Denmark | 12 |
| A Star Is Born | 2000 | Christopher Spencer, José Maria Millet Lopez | Story | 10 | Denmark | 12 |
| Megabioscoop | 2000 | Jan Kruse, Piet Voordes | Story | 2 | Holland | 12 |
| Paperino sostituto inventore | 2000 | Sergio Tulipano, Comicup Studio | Story | 28 | Italy | 12 |
| Paperino e la coppa di Paperopoli | 2000 | Silvano Mezzavilla, Claudio Panarese | Story | 31 | Italy | 12 |
| Never Say Never | 2000 | Spectrum Associates, Antoni Bancells Pujadas | Story | 50 | Denmark | 11 |
| Outback Olympics | 2000 | Laura Shaw, Flemming Andersen | Story | 35 | Denmark | 11 |
| Poezenluik | 2000 | Wilma van den Bosch, Comicup Studio | Story | 1 | Holland | 11 |
| Geld moet rollen! | 2000 | Maarten Janssens | Cover | 1 | Holland | 11 |
| The Secret Origin of the Duck Avenger | 2000 | Michael Stewart, Steven Butler | Story | 10 | Disney Comics | 11 |
| The Tail Feather Trauma | 2000 | Spectrum Associates, José Maria Manrique | Story | 50 | Denmark | 10 |
| Hidden Extras | 2000 | Charlie Martin, José Colomer Fonts | Story | 10 | Denmark | 10 |
| Steine des Anstoßes | 2000 | Pascal Oost, Carry Brugman | Story | 7 | Holland | 10 |
| Rode hoed | 2000 | Jan Kruse, Jaap Stavenuiter | Story | 1 | Holland | 10 |
| Untitled cover | 2000 | Wilma van den Bosch | Cover | 1 | Holland | 10 |
| Paperina e la nonna innamorata | 2000 | Nino Russo, Marco Mazzarello | Story | 19 | Italy | 10 |
| Paure nascoste | 2000 | Bruno Enna, Andrea Ferraris | Story | 1 | Italy | 10 |
| Paperino e le auto restringenti | 2000 | Augusto Macchetto, Marco Meloni | Story | 4 | Italy | 10 |
| Il cappello | 2000 | Angelo Palmas, Michela Frare | Story | 1 | Italy | 10 |
| The 4-D Duck | 2000 | Michael T. Gilbert, José Maria Manrique | Story | 45 | Denmark | 9 |
| Untitled cover | 2000 | Tino Santanach Hernandez | Cover | 1 | Denmark | 9 |
| Bloepers | 2000 | Wilma van den Bosch, Comicup Studio | Story | 8 | Holland | 9 |
| Spookdame | 2000 | Frank Jonker, Sander Gulien | Story | 4 | Holland | 9 |
| Hazeslaapje | 2000 | Loredana Sozanno, Sander Gulien | Story | 4 | Holland | 9 |
| Untitled cover | 2000 | Daan Jippes | Cover | 1 | Holland | 9 |
| Paperino e la risata terapeutica | 2000 | Antonella Pandini, Pier Dario Pennati | Story | 30 | Italy | 9 |
| Paperina e le due litiganti | 2000 | Carlo Panaro, Giampaolo Soldati | Story | 16 | Italy | 9 |
| Si parte! | 2000 | Ilaria Isaia, Marco Meloni | Story | 1 | Italy | 9 |
| Tutti al mare | 2000 | Nino Russo, Giorgio Di Vita | Story | 1 | Italy | 9 |
| Qui, Quo, Qua e la cupola del mistero | 2000 | Augusto Macchetto, Silvio Camboni | Story | 9 | Italy | 9 |
| Untitled cover | 2000 | Francesco Artibani, Corrado Mastantuono | Cover | 1 | Italy | 9 |
| Différences | 2000 | Philippe Larbier | Game or puzzle | 1 | France | 8 |
| Inca's en aardappels | 2000 | Pascal Oost, Comicup Studio | Story | 13 | Holland | 8 |
| Aan één boom zo vol... (Kerst) | 2000 | Jan Kruse, Bas Heymans | Story | 10 | Holland | 8 |
| Paperina e il socio inaspettato | 2000 | Giulia Conti, Paolo Campinoti | Story | 16 | Italy | 8 |
| Paperino e l'inseguimento cellulare | 2000 | Emanuela Negrin | Story | 30 | Italy | 8 |