| Paperin Pigafetta Oltre i confini del mondo | 2021 | Pietro Zemelo, Paolo Mottura | Story | 92 | Italy | 27 |
| Gastone e la solitudine del quadrifoglio | 2021 | Marco Nucci, Stefano Zanchi | Story | 52 | Italy | 26 |
| Paperinik e la minaccia alla fattoria | 2021 | Marco Gervasio, Giuseppe Facciotto | Story | 53 | Italy | 22 |
| A Christmas Coot | 2021 | Marco Nucci, Paolo Mottura | Story | 40 | Italy | 21 |
| In Time For Christmas | 2021 | Knut Nærum, Arild Midthun | Story | 30 | Denmark | 18 |
| Zio Paperone e il profumo del tempo | 2021 | Fabio Michelini, Andrea Ferraris | Story | 22 | Italy | 16 |
| Paperino e il sigillo di Papero Magno | 2021 | Carlo Panaro, Marco Palazzi | Story | 48 | Italy | 16 |
| The Snooze Button | 2021 | Kari Korhonen | Story | 11 | Denmark | 14 |
| Un'ardua impresa | 2021 | Tito Faraci, Luca Bonardi | Story | 1 | Italy | 14 |
| Fitness e cocomeri | 2021 | Alessio Coppola | Story | 1 | Italy | 14 |
| Helping Hands | 2021 | Lars Jensen, Angel Rodriguez | Story | 4 | Denmark | 13 |
| Heroes of the Myth | 2021 | Jaakko Seppälä, Francisco Rodriguez Peinado | Story | 10 | Denmark | 13 |
| Inseguimento fallimentare | 2021 | Tito Faraci, Luca Bonardi | Story | 1 | Italy | 13 |
| More than Medals | 2021 | Frauke Schmickl, Sebastián Puñales | Story | 5 | Denmark | 12 |
| A Visit to Grubkcud | 2021 | Jaakko Seppälä, Cèsar Ferioli Pelaez | Story | 10 | Denmark | 11 |
| Owl's Well that Ends Well | 2021 | Carol McGreal, Joan Crexells Aparicio | Story | 2 | Denmark | 11 |
| The Masked Knight | 2021 | Stefano Ambrosio, Lorenzo Pastrovicchio | Story | 22 | Disney Publishing Worldwide (global) | 11 |
| The Curse of the Endless Rain | 2021 | Alessandro Gatti, Alessandro Pastrovicchio | Story | 22 | Disney Publishing Worldwide (global) | 11 |
| The Guardian of the Abyss | 2021 | Riccardo Pesce, Ciro Cangialosi | Story | 22 | Disney Publishing Worldwide (global) | 11 |
| The Tournament of the Medlar | 2021 | Alessandro Gatti, Marco Mazzarello | Story | 22 | Disney Publishing Worldwide (global) | 11 |
| The Cauldron of Discord | 2021 | Riccardo Pesce, Luca Usai | Story | 22 | Disney Publishing Worldwide (global) | 11 |
| The Lying Ballads | 2021 | Alessandro Gatti, Lorenzo Pastrovicchio | Story | 22 | Disney Publishing Worldwide (global) | 11 |
| The New Knight | 2021 | Alessandro Ferrari, Alessandro Pastrovicchio | Story | 22 | Disney Publishing Worldwide (global) | 11 |
| A Ring from the Past | 2021 | Gorm Transgaard, Carlos Mota | Story | 4 | Denmark | 10 |
| Pumpkin Kings | 2021 | Andreas Pihl, Marco Rota | Story | 10 | Denmark | 10 |
| Donald Goes Viral | 2021 | Maya Åstrup, Francisco Rodriguez Peinado | Story | 10 | Denmark | 10 |
| Hidden Talent | 2021 | Maya Åstrup, Angel Rodriguez | Story | 5 | Denmark | 10 |
| Pie in the Sky | 2021 | Carol McGreal, Maria José Sánchez Núñez | Story | 5 | Denmark | 10 |
| Mysterious Digits | 2021 | Gaute Moe, Carmen Pérez | Story | 10 | Denmark | 9 |
| Gus Quixote | 2021 | Jaakko Seppälä, Fernando Güell | Story | 6 | Denmark | 9 |
| Gus the Giant | 2021 | Peter Snejbjerg, Carmen Pérez | Story | 5 | Denmark | 9 |
| Paperino Billy e il blunevoso svolazzatore | 2021 | Davide Aicardi, Giampaolo Soldati | Story | 16 | Italy | 9 |
| Paperino & l'ultima voce della lista | 2021 | Francesco Vacca, Francesco Guerrini | Story | 22 | Italy | 9 |
| Christmas Tree Trouble | 2021 | Carol McGreal, Wanda Gattino | Story | 10 | Denmark | 8 |
| Luiervakantie | 2021 | Hugo Sauer, Jordi Alfonso | Story | <1 | Holland | 8 |
| De slapende oma | 2021 | Frank Jonker, Maria José Sánchez Núñez | Story | 4 | Holland | 8 |
| De appeltaartdief | 2021 | Frank Jonker, José Antonio González | Story | 3 | Holland | 8 |
| Het afspraakje | 2021 | Robbert Damen, Thomas Cabellic | Story | 4 | Holland | 8 |
| Zio Paperone e la Gazzella del Nord | 2021 | Vito Stabile, Marco Rota | Story | 26 | Italy | 8 |
| Il barocco | 2021 | Augusto Macchetto, Emilio Urbano | Story | 27 | Italy | 8 |
| Untitled illustration | 2021 | Blasco Pisapia | Illustration | 1 | Italy | 8 |
| Stop and Smell the Produce | 2021 | Carol McGreal, Maria José Sánchez Núñez | Story | 3 | Denmark | 7 |
| Hoefijzer | 2021 | Gerard Leever, Jordi Alfonso | Story | 1 | Holland | 7 |
| Oma's jeugdliefde | 2021 | Gerard Leever, Daniel Pérez | Story | 10 | Holland | 7 |
| De tractor | 2021 | Gerard Leever, José Antonio González | Story | 4 | Holland | 7 |
| Weekje gezond 2 | 2021 | Hugo Sauer, José Antonio González | Story | <1 | Holland | 6 |
| De Zotskapspelen | 2021 | Frank Jonker, Jordi Alfonso | Story | 10 | Holland | 6 |
| Ijverige droom | 2021 | Willem Ritstier, Pablo Reche | Story | 2 | Holland | 6 |
| de gluiperige sluipwesp | 2021 | Robbert Damen, Tim Artz | Story | 8 | Holland | 6 |
| Topo Principe | 2021 | Augusto Macchetto, Giada Perissinotto | Story | 50 | Italy | 6 |
| Zio Paperone e le case mobili | 2021 | Fabio Michelini, Marco Palazzi | Story | 24 | Italy | 6 |
| Untitled cover | 2021 | | Cover | 1 | Denmark | 5 |
| Voedertijd | 2021 | Ruud Straatman, Bas Heymans | Story | 1 | Holland | 5 |
| Portret van Gijs | 2021 | Hugo Sauer, Jordi Alfonso | Story | <1 | Holland | 5 |
| Sapcentrifuge | 2021 | Wouter Goudswaard, José Antonio González | Story | 2 | Holland | 5 |
| De verdwenen noten | 2021 | Frank Jonker, Daniel Pérez | Story | 3 | Holland | 5 |
| Videocall | 2021 | Remco Polman, José Antonio González | Story | <1 | Holland | 4 |
| Weekje voetbal 2 | 2021 | Willem Ritstier, Carmen Pérez | Story | <1 | Holland | 4 |
| Belletje | 2021 | Jana van de Hoek, Carmen Pérez | Story | 1 | Holland | 4 |
| Zio Paperone e l'oro dell'Aurosauro | 2021 | Fabio Michelini, Giulia La Torre | Story | 36 | Italy | 4 |