| Smokey from ZS 39-07-09 | 1939 | | 0 | 1 |
| Smudge | 1975 | | 0 | 1 |
| Smulan | 2011 | | 0 | 1 |
| Snacky Squirrel | 1959 | | 0 | 1 |
| Snagg & Ripp | 1977 | | 0 | 1 |
| Snagg from W DG 55-03 | 1961 | | 0 | 1 |
| Snail from H 85116 | 1987 | | 0 | 1 |
| Snail's children | 1969 | | 0 | 1 |
| Snake Eyes McViper | 1949 | | 0 | 1 |
| Snappy from Toy Story | 2026 | | 0 | 1 |
| Snark Batfly | 1980 | | 0 | 1 |
| Snarlin Grando | 1961 | | 0 | 1 |
| Sneekly | 1975 | | 0 | 1 |
| Sneezer the burro | 1959 | | 0 | 1 |
| Sniffer the bloodhound | 1955 | | 0 | 1 |
| Snip from W MM 32-02 | 1953 | | 0 | 1 |
| Snodgrass sisters | 1966 | | 0 | 1 |
| Snookums | 1996 | | 1 | 1 |
| Snorky | 2023 | | 0 | 1 |
| Snowball from 101 Dalmatian Street | 2019 | | 0 | 1 |
| Snowy the abominable snowwoman | 2011 | | 0 | 1 |
| Snørrbahrt | 2007 | | 0 | 1 |
| Sofi | 2023 | | 0 | 1 |
| Sofia from B 810029 | 1981 | | 0 | 1 |
| Sofia from B 900013 | 1991 | | 0 | 1 |
| Sofia from B 910241 | 1992 | | 0 | 1 |
| Sofia from B 980003 | 1998 | | 0 | 1 |
| Sonado from B RJC 014 | 1962 | | 0 | 1 |
| Sondra | 2008 | | 0 | 1 |
| Sondra Malik | 1999 | | 0 | 1 |
| Sonja Costanza | 2015 | | 0 | 1 |
| Sonja Henie | 1939 | | 0 | 1 |
| Sonny the photographer | 2022 | | 0 | 1 |
| Sonny the skunk | 1976 | | 0 | 1 |
| Sonífero Z. Insônio | 1991 | | 0 | 1 |
| Soop | 2006 | | 0 | 1 |
| Sophia the householder robot | 1982 | | 0 | 1 |
| Sophie Shoplifter | 1972 | | 0 | 1 |
| Soshiro Sarsicha | 1993 | | 0 | 1 |
| Sovereign | 2024 | | 0 | 1 |
| Sow bug | 1972 | | 0 | 1 |
| Sow bug from SC | 1967 | | 0 | 1 |
| Spadino | 2023 | | 0 | 1 |
| Spagnoletta | 1996 | | 1 | 1 |
| Spaniel | 1974 | | 0 | 1 |
| Spare Mint | 2021 | | 0 | 1 |
| Spark | 2014 | | 0 | 1 |
| Sparky | 2003 | | 0 | 1 |
| Spears | 2012 | | 0 | 1 |
| Speedy the hamster | | | 0 | 1 |
| Speedy's pop | 1958 | | 0 | 1 |
| Spider from H 92196 | 1993 | | 0 | 1 |
| Spider from H 93039 | 1994 | | 0 | 1 |
| Spider-Man | 2025 | | 0 | 1 |
| SpielBlergh | 1995 | | 0 | 1 |
| Spik the robot | 1993 | | 0 | 1 |
| Spike | 2011 | | 0 | 1 |
| Spike McGoul | 1958 | | 0 | 1 |
| Spike and Dimitri | 2007 | | 0 | 1 |
| Spike from W DD 70-04 | 1960 | | 0 | 1 |
Grandpa Beagle
Aunt Melinda
Biquinho
Humphrey Gokart
Brer Rabbit
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