| Untitled illustration | 1980 | Christo (born 1923) | Illustration | | France | 40 |
| The Magic Mystery | 1980 | Paul Murry | Story | 6 | Western | 38 |
| Detective Pluto | 1980 | Paul Murry | Story | 8 | Western | 38 |
| The Riverboat Mystery | 1980 | Paul Murry | Story | 8 | Western | 38 |
| The Cat's Meow | 1980 | Paul Murry | Story | 8 | Western | 37 |
| The Crown Of Crephillia | 1980 | Bob Bartholomew, Josep Tello Gonzalez | Story | 15 | Denmark | 36 |
| Hold-up In Wild Westland | 1980 | Tom Anderson, Antoni Bancells Pujadas | Story | 16 | Denmark | 35 |
| Topolino e il ricattatore misterioso | 1980 | Rudy Salvagnini, Massimo De Vita | Story | 36 | Italy | 35 |
| Topolino e il fiore magico | 1980 | Guido Martina, Massimo De Vita | Story | 34 | Italy | 33 |
| Mission to Planet Zoa | 1980 | Paul Murry | Story | 18 | Western | 33 |
| La course au flambeau ! | 1980 | Daniel Pecqueur, Claude Marin | Story | 68 | France | 32 |
| Topolino e il messaggio del re | 1980 | Gian Giacomo Dalmasso, Pepe Ferré | Story | 59 | Italy | 32 |
| Topolino e il dilemma dei cargo | 1980 | Romano Scarpa | Story | 35 | Italy | 31 |
| The Giant Bear | 1980 | Tom Anderson, Antoni Bancells Pujadas | Story | 10 | Denmark | 30 |
| Check That Chicken | 1980 | Tom Anderson, Antoni Bancells Pujadas | Story | 13 | Denmark | 29 |
| Topolino e lo straordinario "Stravigarius" | 1980 | Romano Scarpa | Story | 66 | Italy | 28 |
| Topolino e l'allucinante "caso" dei furti impossibili | 1980 | Bruno Concina, Massimo De Vita | Story | 66 | Italy | 28 |
| Κλασικά. Περιεχόμενα | 1980 | | Text story | 1 | Non-Disney and/or non-comics | 28 |
| The Worst Of The West | 1980 | Jaime Diaz Studio | Story | 11 | Disney Studio (foreign market stories) | 28 |
| Bees A-Buzzing! | 1980 | Jim Kenner, Miquel Pujol | Story | 6 | Denmark | 27 |
| The UFO Mystery | 1980 | Jim Kenner, Josep Tello Gonzalez | Story | 14 | Denmark | 27 |
| Aunt Tessie-svengali | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 10 | Disney Studio (foreign market stories) | 26 |
| The Risky Wreck | 1980 | Howard Swift, Jaime Diaz Studio | Story | 10 | Disney Studio (foreign market stories) | 26 |
| Untitled newspaper strip | 1980 | Del Connell, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 26 |
| Neighborhood Smiles | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 10 | Disney Studio (foreign market stories) | 25 |
| Showdown In Dry Gulch | 1980 | Tom Anderson, Josep Tello Gonzalez | Story | 9 | Denmark | 24 |
| Topolino e la banda del black-out | 1980 | Rudy Salvagnini, Giovan Battista Carpi | Story | 33 | Italy | 24 |
| The Rattle Mystery | 1980 | Jim Kenner, Antoni Bancells Pujadas | Story | 7 | Denmark | 23 |
| The Mysterious Jar | 1980 | Bob Bartholomew, Josep Tello Gonzalez | Story | 10 | Denmark | 23 |
| Pop Mystery | 1980 | Tom Anderson, Antoni Bancells Pujadas | Story | 8 | Denmark | 23 |
| Topolino e il terrore di Topolunia | 1980 | Guido Martina, Sergio Asteriti | Story | 35 | Italy | 23 |
| The Mystery on the Mesa | 1980 | Paul Murry | Story | 8 | Western | 23 |
| TV Mystery | 1980 | Tom Anderson, Josep Tello Gonzalez | Story | 6 | Denmark | 22 |
| Topolino e la quiete lacustre | 1980 | Romano Scarpa | Story | 35 | Italy | 22 |
| The Great Skateboard Diamond Chase | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 17 | Disney Studio (foreign market stories) | 22 |
| Pluto's Who's Who? | 1980 | Howard Swift, Jaime Diaz Studio | Story | 12 | Disney Studio (foreign market stories) | 22 |
| Black Arts | 1980 | Tom Anderson, Josep Tello Gonzalez | Story | 11 | Denmark | 21 |
| Topolino e il fantomatico ritorno di Macchia Nera | 1980 | Rudy Salvagnini, Massimo De Vita | Story | 33 | Italy | 21 |
| Trim And Tingly Ranch | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 10 | Disney Studio (foreign market stories) | 21 |
| The Riches Of Ramarkan | 1980 | Bob Bartholomew, Josep Tello Gonzalez | Story | 11 | Denmark | 20 |
| Goofy Baby Sitter | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 10 | Disney Studio (foreign market stories) | 20 |
| Goofy Birds | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 9 | Disney Studio (foreign market stories) | 20 |
| Topolino e la mappa misteriosa | 1980 | Guido Martina, Giovan Battista Carpi | Story | 18 | Italy | 19 |
| Topolino e l'usurpatore | 1980 | Anne-Marie Dester, Miquel Pujol | Story | 38 | Italy | 19 |
| The Monster Of Lake Tiddy-wah-wah | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 21 | Disney Studio (foreign market stories) | 19 |
| Let It Rain - Let It Shine | 1980 | Ed Nofziger, Jack Bradbury | Story | 8 | Disney Studio (foreign market stories) | 19 |
| Big Fish | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 11 | Disney Studio (foreign market stories) | 19 |
| Bigger 'n' Big | 1980 | Howard Swift, Jaime Diaz Studio | Story | 13 | Disney Studio (foreign market stories) | 19 |
| The Big Escape | 1980 | Bob Langhans, Jaime Diaz Studio | Story | 11 | Disney Studio (foreign market stories) | 19 |
| Hypnotic Goofy | 1980 | Jack Manning | Story | 6 | Western | 19 |
| Untitled newspaper strip | 1980 | Del Connell, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 19 |
| Untitled newspaper strip | 1980 | Del Connell, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 19 |
| Under Siege | 1980 | Tom Anderson, Josep Tello Gonzalez | Story | 8 | Denmark | 18 |
| Untitled illustration | 1980 | François Pasquet | Illustration | <1 | France | 18 |
| Untitled illustration | 1980 | Pierre Nicolas | Illustration | <1 | France | 18 |
| The Day Super Goof Goofed | 1980 | Howard Swift, Cliff Voorhees | Story | 14 | Disney Studio (foreign market stories) | 18 |
| The Case Of The Cruise | 1980 | Cal Howard | Story | 44 | Disney Studio (foreign market stories) | 18 |
| Party At Goofys | 1980 | Ed Nofziger, Jaime Diaz Studio | Story | 10 | Disney Studio (foreign market stories) | 18 |
| All Downhill To Junction City | 1980 | Howard Swift, Jaime Diaz Studio | Story | 12 | Disney Studio (foreign market stories) | 18 |
| Untitled newspaper strip | 1980 | Del Connell, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 18 |