| Untitled cover | 2000 | Don Rosa | Cover | 1 | Finland | 42 |
| Good-Bye To All That | 2000 | Kari Korhonen, Tino Santanach Hernandez | Story | 18 | Denmark | 33 |
| Prophets, Go Home! | 2000 | Kari Korhonen | Story | 6 | Denmark | 32 |
| La rivincita di Paperamses | 2000 | Davide Catenacci, Giuseppe Dalla Santa | Story | 29 | Italy | 30 |
| Cosmic Confrontation | 2000 | John Blair Moore, Flemming Andersen | Story | 39 | Denmark | 29 |
| The Dream Helmet | 2000 | Christopher Spencer, José Maria Millet Lopez | Story | 8 | Denmark | 27 |
| Idool | 2000 | Evert Geradts, Mau Heymans | Story | 10 | Holland | 27 |
| Paperino e l'amaca da sogno | 2000 | Giustina Porcelli, Marco Pavone | Story | 12 | Italy | 27 |
| 8 | 2000 | Don Rosa | Illustration | 1 | Denmark | 25 |
| Intellettuale-176 genio incompreso | 2000 | Alessandro Sisti, Giorgio Cavazzano | Story | 21 | Italy | 25 |
| Robot Run-Around | 2000 | Carol McGreal, Vicar | Story | 12 | Denmark | 24 |
| Archimede e il rivale imbattibile | 2000 | Rudy Salvagnini, Giorgio Cavazzano | Story | 29 | Italy | 24 |
| Archimede e la spedizione all'eurekannone | 2000 | Augusto Macchetto, Giampaolo Soldati | Story | 22 | Italy | 24 |
| Archimede e la valle che canta | 2000 | Stefano Ambrosio, Andrea Freccero | Story | 27 | Italy | 24 |
| Don Rosan olympiajuliste | 2000 | Don Rosa | Illustration | 1 | Finland | 24 |
| Bionic Benny | 2000 | Paul Halas, José Maria Millet Lopez | Story | 8 | Denmark | 23 |
| A Bit Of A Wizard | 2000 | Charlie Martin, José Colomer Fonts | Story | 16 | Denmark | 22 |
| Time Isn't Money | 2000 | Christopher Spencer, Ignasi Calvet Estéban | Story | 11 | Denmark | 22 |
| Untitled cover | 2000 | Tello-Team | Cover | 1 | Denmark | 21 |
| Can I Bring Anything? | 2000 | Kari Korhonen | Story | 14 | Denmark | 20 |
| Archimede e la zia a sorpresa | 2000 | Giustina Porcelli, Lara Molinari | Story | 27 | Italy | 20 |
| Weird Science | 2000 | Dave Rawson, Massimo Fecchi | Story | 35 | Denmark | 19 |
| Archimede e la bottega delle invenzioni impossibili | 2000 | Stefano Ambrosio, Marco Palazzi | Story | 25 | Italy | 19 |
| Paperino e la sveglia cangiante | 2000 | Giustina Porcelli, Enrico Faccini | Story | 12 | Italy | 19 |
| Edi, Gennarino e la rivincita degli aiutanti | 2000 | Gaja Arrighini, Giampaolo Soldati | Story | 22 | Italy | 17 |
| Zio Paperone & il deposito innamorato | 2000 | Francesco Guerrini | Story | 29 | Italy | 17 |
| Open Sesame | 2000 | Paul Halas, José Maria Millet Lopez | Story | 12 | Denmark | 16 |
| Dr. Jekyll | 2000 | Frank Jonker, Comicup Studio | Story | 4 | Holland | 16 |
| Zio Paperone, Archimede e la corsa terrestre | 2000 | Giorgio Martignoni, Roberto Marini | Story | 32 | Italy | 16 |
| als wethouder | 2000 | Jan Kruse, Bas Heymans | Story | 10 | Holland | 15 |
| The Runaway Duckling | 2000 | Gorm Transgaard, Ignasi Calvet Estéban | Story | 12 | Denmark | 14 |
| Vikingen | 2000 | Evert Geradts, Santiago Barreira | Story | 5 | Holland | 14 |
| La richiesta di Qui, Quo, Qua | 2000 | Sergio Tulipano, Francesco Guerrini | Story | 6 | Italy | 14 |
| Paperone e l'operazione salvadanaio | 2000 | Fabio Michelini, Valerio Held | Story | 32 | Italy | 14 |
| The Power Of Balance | 2000 | John Blair Moore, Antoni Bancells Pujadas | Story | 26 | Denmark | 13 |
| Hologram Horrors | 2000 | Paul Halas, José Maria Millet Lopez | Story | 7 | Denmark | 13 |
| Paperino sostituto inventore | 2000 | Sergio Tulipano, Comicup Studio | Story | 28 | Italy | 12 |
| Geld moet rollen! | 2000 | Maarten Janssens | Cover | 1 | Holland | 11 |
| Paperino e le auto restringenti | 2000 | Augusto Macchetto, Marco Meloni | Story | 4 | Italy | 10 |
| The 4-D Duck | 2000 | Michael T. Gilbert, José Maria Manrique | Story | 45 | Denmark | 9 |
| La proposta di Paperone | 2000 | Sergio Tulipano, Francesco Guerrini | Story | 6 | Italy | 9 |
| Το σταυρόλεξο του Γλόμπου | 2000 | | Game or puzzle | 1 | Non-Disney and/or non-comics | 9 |
| La soluzione per... Archimede | 2000 | Sergio Tulipano, Francesco Guerrini | Story | 6 | Italy | 8 |
| Qui Quo Qua e la fotografia rivelatrice | 2000 | Carlo Panaro, Marco Mazzarello | Story | 26 | Italy | 8 |
| Weird Inventions 15 | 2000 | Don Rosa | Illustration | <1 | Finland | 8 |
| Carnaval Fora de Época | 2000 | Gérson Luiz Borlotti Teixeira, Eli Marcos M. Leon | Story | 10 | Brazil | 7 |
| Il problema di Paperina | 2000 | Sergio Tulipano, Francesco Guerrini | Story | 6 | Italy | 7 |
| Untitled game or puzzle | 2000 | Studio Bonnet | Game or puzzle | 1 | Denmark | 6 |
| Paperino e la mezzanotte contesa | 2000 | Gianfranco Cordara, Enrico Faccini | Story | 31 | Italy | 6 |
| Paperino e l'energia cosmica | 2000 | Carlo Panaro, Luciano Gatto | Story | 28 | Italy | 6 |
| Tales from the Bin 39 | 2000 | Don Rosa | Illustration | <1 | Finland | 6 |
| Géo, dino, bobo | 2000 | François Corteggiani, Rachid Nawa | Story | 8 | France | 5 |
| Mixed results - Résultats mitigés | 2000 | Jean-Paul Jennequin, Philippe Larbier | Story | 1 | France | 5 |
| Mars | 2000 | José Antonio González | Illustration | 1 | France | 4 |
| Novembre - Dicembre 2000 | 2000 | Luciano Bottaro | Illustration | 1 | Italy | 4 |
| Dialect Album Story | 2000 | Klaus Mühlsteffen, Vicar | Story | 2 | Denmark | 3 |
| Untitled cover | 2000 | Lorenzo Pastrovicchio | Cover | 1 | Italy | 3 |
| Donald's trukendoos | 2000 | | Game or puzzle | 1 | Holland | 2 |
| Donald's trukendoos | 2000 | | Game or puzzle | 1 | Holland | 2 |
| Donald's trukendoos | 2000 | | Game or puzzle | 1 | Holland | 2 |