| The Pirate Submarine | 1935 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 84 | Daily strips (US) | 711 |
| Tutto questo accadde domani | 2018 | Casty | Story | 88 | Italy | 75 |
| Мика у Београду | 1936 | Vlastimir Belkić | Story | 23 | Yugoslavia | 46 |
| Topolino e l'incredibile avventura | 1988 | Giorgio Pezzin, Giampiero Ubezio | Story | 55 | Italy | 32 |
| Topolino e l'isola dei sogni fuggenti | 1982 | Caterina Mognato, Cèsar Ferioli Pelaez | Story | 28 | Italy | 24 |
| Topolino e i sogni ricorrenti | 1994 | Rudy Salvagnini, Valerio Held | Story | 38 | Italy | 23 |
| Il rustico cavallerizzo | 2015 | Teresa Radice, Stefano Turconi | Story | 42 | Italy | 23 |
| Topo Maltese - Una ballata del topo salato | 2017 | Bruno Enna, Giorgio Cavazzano | Story | 80 | Italy | 23 |
| Un sortilegio in sorte | 2017 | Tito Faraci, Silvia Ziche | Story | 64 | Italy | 22 |
| Raceworld | 2014 | Roberto Gagnor, Claudio Sciarrone | Story | 160 | Italy | 21 |
| Back In The Box | 2004 | Stefan Petrucha, Flemming Andersen | Story | 20 | Denmark | 18 |
| Topolino e il ritorno dell'artiglio magnetico | 1959 | Guido Martina, Giulio Chierchini | Story | 82 | Italy | 18 |
| Topolino e il mistero dei satelliti | 1982 | Alessandro Sisti, Sergio Asteriti | Story | 27 | Italy | 18 |
| La sfida di Fantomius | 2017 | Marco Gervasio | Story | 30 | Italy | 18 |
| Mickey Mouse and the Pirate Submarine | 1993 | Floyd Gottfredson | Lithograph | 1 | Miscellaneous | 17 |
| Mickey Maltese | 2017 | Giorgio Cavazzano | Cover | 1 | Italy | 17 |
| Che avventure, Topolino! | 2018 | Casty | Story | 16 | Italy | 14 |
| Cari, vecchi, "storici" personaggi | 1970 | Mario Gentilini, Al Taliaferro | Article | 3 | Non-Disney and/or non-comics | 14 |
| The Past-Imperfect | 1998 | David Gerstein, Cèsar Ferioli Pelaez | Story | 14 | Denmark | 12 |
| L'altra faccia di Gambadilegno | 1998 | Fabio Michelini, Roberto Vian | Story | 27 | Italy | 12 |
| Topolino e il segreto di Basettoni | 1995 | Angelo Palmas, Andrea Ferraris | Story | 62 | Italy | 11 |
| Topolino e il tricorno degli Otto Mari | 2019 | Matteo Venerus, Davide Baldoni | Story | 34 | Italy | 11 |
| Untitled cover | 1987 | Daan Jippes | Cover | 1 | Another Rainbow (Gladstone) | 9 |
| Mickey contre l'alliance maléfique | 2024 | Nicolas Pothier, Johan Pilet | Story | 52 | France | 9 |
| Il giro dei mondi in 80 giorni (siderali) | 2018 | Fausto Vitaliano, Lorenzo Pastrovicchio | Story | 81 | Italy | 9 |
| Operazione Zeus | 2023 | Marco Gervasio, Emmanuele Baccinelli | Story | 118 | Italy | 8 |
| Mickey contre l'alliance maléfique | 2024 | Johan Pilet | Cover | 1 | France | 7 |
| Topolino e il mistero del museo degli orrori | 2022 | Marco Nucci, Casty | Story | 22 | Italy | 7 |
| I grandi avversari... ...e i tipi curiosi | 1982 | Luciano Bottaro | Story | 2 | Italy | 7 |
| Untitled cover | 1985 | Floyd Gottfredson, Romano Scarpa | Cover | 1 | Italy | 7 |
| Untitled cover | 1936 | | Cover | 1 | Italy | 6 |
| Io & Minni | 2018 | Giorgio Fontana, Massimo De Vita | Story | 30 | Italy | 5 |
| Mickey 70 | 1998 | Lewis Trondheim | Story | 1 | Non-Disney and/or non-comics | 5 |
| Topolino e la sfida dei 70 anni | 1998 | Fabio Michelini, Giovan Battista Carpi | Story | 30 | Italy | 4 |
| Topolino e la popolarità ingombrante | 2018 | Federico Rossi Edrighi, Nicola Tosolini | Story | 30 | Italy | 4 |
| Untitled cover | 1967 | | Cover | 1 | Italy | 4 |
| Untitled illustration | 1994 | Lello Arena, Francesco Artibani | Illustration | <1 | Italy | 4 |
| Untitled cover | 2022 | Corrado Mastantuono | Cover | 1 | Italy | 4 |
| Attenti a Gambadilegno! | 2023 | Federico Butticè | Illustration | 2 | Italy | 3 |
| Untitled cover | 1988 | Franco Bruna | Cover | 1 | Italy | 3 |
| Untitled illustration | 1992 | Giovan Battista Carpi | Illustration | <1 | Italy | 3 |
| Untitled cover | 1936 | | Cover | 1 | Yugoslavia | 3 |
| Untitled illustration | 2011 | Jan-Roman Pikula | Illustration | 2 | Holland | 2 |
| Topolino e il flagello dei mari | 1955 | | Story | 48 | Italy | 2 |
| Galleria di Topolino | 1959 | Floyd Gottfredson | Cover | 1 | Italy | 2 |
| The Mickey Mouse Scrapbook 1928-1978 | 1977 | | Illustration | 2 | United Kingdom | 2 |
| Мика боксер | 1936 | Vlastimir Belkić | Story | 2 | Yugoslavia | 2 |
| Énigmettes | 2020 | Virgile Turier, David Augereau | Story | 2 | France | 1 |
| le mystère du musée des horreurs | 2023 | Casty | Cover | 1 | France | 1 |
| Topolinia party | 2024 | Rudy Salvagnini, Luca Usai | Story | 22 | Italy | 1 |
| Prologo | 2017 | Massimo Marconi, Salvatore Deiana | Story | 20 | Italy | 1 |
| Untitled cover | 1993 | Franco Bruna | Cover | 1 | Italy | 1 |
| Untitled illustration | 2024 | Casty | Illustration | | Italy | 1 |
| Untitled illustration | 2025 | Giorgio Cavazzano | Illustration | | Italy | 1 |
| Untitled illustration | 2025 | Lorenzo Pastrovicchio | Illustration | 1 | Italy | 1 |
| Untitled illustration | 2025 | Casty | Illustration | <1 | Italy | 1 |
| Untitled illustration | 2025 | Casty | Illustration | 1 | Italy | 1 |
| Untitled illustration | 2025 | Casty | Illustration | <1 | Italy | 1 |
| Untitled cover | 2015 | Corrado Mastantuono | Cover | 1 | Italy | 1 |
| Untitled cover | 1971 | Marco Rota | Cover | 1 | Italy | 1 |