| Pluto in Love Trouble | 1955 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 30 | Daily strips (US) | 127 |
| The Talking Dog | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 125 |
| The Sorcerer of Donnybrook Castle | 1969 | Alpine Harper, Paul Murry | Story | 24 | Western | 113 |
| The Mystery Monster from Smoggy Bog | 1972 | Paul Murry | Story | 24 | Western | 103 |
| The Sign of the Scorpion | 1970 | Paul Murry | Story | 24 | Western | 101 |
| The Case of the Dazzling Hoo-Doo | 1968 | Carl Fallberg, Paul Murry | Story | 24 | Western | 99 |
| Adventures With Robin Hood | 1955 | Ted Osborne, Jack Bradbury | Story | 40 | Western | 96 |
| The Shattered-Glass Mystery | 1952 | Riley Thomson | Story | 24 | Western | 90 |
| Pluto the Pup | 1931 | Floyd Gottfredson | Newspaper strip | 10 | Daily strips (US) | 87 |
| Nobody's Business | 1987 | Don Rosa | Story | 10 | Another Rainbow (Gladstone) | 86 |
| The Fiendish Cat | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 84 |
| Morty's Escapade | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 82 |
| Saves the Ship | 1942 | Carl Barks, Bruce Bushman | Story | 51 | Western | 81 |
| Pluto and the Dogcatcher | 1933 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 13 | Daily strips (US) | 80 |
| als leeuw! | 1954 | Don Christensen, Paul Murry | Story | 6 | Western | 78 |
| Untitled newspaper strip | 1946 | Bill Walsh, Paul Murry | Newspaper strip | 6 | Daily strips (US) | 76 |
| Tutto questo accadde domani | 2018 | Casty | Story | 88 | Italy | 75 |
| Pflip the Thnuckle-booh | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 18 | Daily strips (US) | 75 |
| Friends from Duckburg/Mouseton | 2018 | | Illustration | 2 | Disney Publishing Worldwide (global) | 70 |
| This Is Your Life, Donald Duck | 1960 | Vic Lockman, Tony Strobl | Story | 31.9 | Western | 68 |
| Pluto's Rival | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 10 | Daily strips (US) | 68 |
| Untitled newspaper strip | 1939 | Hubie Karp, Bob Grant | Newspaper strip | 1 | Sunday pages (US) | 68 |
| Caws and Effect | 1953 | Don Christensen, Paul Murry | Story | 6 | Western | 67 |
| Untitled newspaper strip | 1935 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 1 | Sunday pages (US) | 67 |
| The War Orphans | 1944 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 30 | Daily strips (US) | 66 |
| Untitled newspaper strip | 1949 | Bill Walsh, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 66 |
| Green Dogs and Jams | 1953 | Paul Murry | Story | 7 | Western | 65 |
| Untitled newspaper strip | 1947 | Bill Walsh, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 65 |
| Topolino e il mistero della voce spezzata | 1991 | Silvano Mezzavilla, Giorgio Cavazzano | Story | 52 | Italy | 64 |
| Topolino e il fiume del tempo | 1998 | Francesco Artibani, Corrado Mastantuono | Story | 50 | Italy | 64 |
| An Education for Thursday | 1960 | Merrill De Maris, Paul Murry | Story | 40 | Western | 64 |
| Flight of the Dragon | 1973 | Alpine Harper, Paul Murry | Story | 24 | Western | 64 |
| Untitled newspaper strip | 1932 | Floyd Gottfredson | Newspaper strip | 1 | Sunday pages (US) | 64 |
| Untitled newspaper strip | 1949 | Bill Walsh, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 64 |
| The Day the Mountain Shook | 1992 | Carl Barks, Daan Jippes | Story | 13 | Holland | 63 |
| L'isola dei misteri | 2020 | Francesco Artibani, Lorenzo Pastrovicchio | Story | 74 | Italy | 63 |
| Boulimie... ckey | 1962 | Pierre Fallot, Pierre Nicolas | Story | 8 | France | 62 |
| The Cure for Hiccups | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 62 |
| Untitled newspaper strip | 1939 | Hubie Karp, Bob Grant | Newspaper strip | 1 | Sunday pages (US) | 62 |
| Pluto | 1953 | Paul Murry | Story | 2 | Western | 61 |
| Amor Canino é Um Cano | 1954 | Don Christensen, Paul Murry | Story | 6 | Western | 61 |
| Mickey's Menagerie | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 61 |
| Untitled newspaper strip | 1949 | Bill Walsh, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 61 |
| Untitled newspaper strip | 1937 | Ted Osborne, Al Taliaferro | Newspaper strip | 1 | Sunday pages (US) | 61 |
| A Whistle in the Dark | 1974 | Paul Murry | Story | 16 | Western | 60 |
| Triple Image | 1956 | Paul Murry | Story | 6 | Western | 60 |
| Eviction | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 60 |
| Auzares de Um Herói | 1953 | Carl Fallberg, Paul Murry | Story | 5 | Western | 59 |
| The Mystery Next Door | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 18 | Daily strips (US) | 59 |
| Untitled newspaper strip | 1932 | Floyd Gottfredson | Newspaper strip | 1 | Sunday pages (US) | 59 |
| Untitled newspaper strip | 1932 | Floyd Gottfredson | Newspaper strip | 1 | Sunday pages (US) | 59 |
| Untitled newspaper strip | 1937 | Ted Osborne, Al Taliaferro | Newspaper strip | 1 | Sunday pages (US) | 59 |
| Untitled newspaper strip | 1939 | Merrill De Maris, Al Taliaferro | Newspaper strip | 1 | Sunday pages (US) | 59 |
| 60 anni insieme con Topolino | 1993 | Luca Boschi, Andrea Ferraris | Story | 88 | Italy | 58 |
| The Case of the Disappearing Diamonds | 1966 | Bob Ogle, Paul Murry | Story | 32 | Western | 58 |
| Untitled newspaper strip | 1939 | Hubie Karp, Bob Grant | Newspaper strip | 1 | Sunday pages (US) | 58 |
| Untitled newspaper strip | 1939 | Hubie Karp, Bob Grant | Newspaper strip | 1 | Sunday pages (US) | 58 |
| Untitled newspaper strip | 1939 | Hubie Karp, Bob Grant | Newspaper strip | 1 | Sunday pages (US) | 58 |
| A 1934 Belchfire Runabout | 1984 | Carl Barks | Lithograph | 1 | Miscellaneous | 57 |
| A Mickey Mystery | 2013 | Byron Erickson, Cèsar Ferioli Pelaez | Story | 22 | Denmark | 57 |