| Westward Whoa! | 1953 | Paul Murry | Story | 17 | Western | 88 |
| The Secret of Shipnappers' Cove | 1969 | Paul Murry | Story | 24 | Western | 88 |
| Pluto the Pup | 1931 | Floyd Gottfredson | Newspaper strip | 10 | Daily strips (US) | 87 |
| Horace's Nerves | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 87 |
| Trapped in Time | 1967 | Alpine Harper, Paul Murry | Story | 40 | Western | 84 |
| Tom-tom Island | 1950 | Riley Thomson | Story | 29 | Western | 83 |
| The Mystery of the Counterfeit Masters | 1970 | Paul Murry | Story | 24 | Western | 79 |
| Mickey Mouse Music | 1930 | Floyd Gottfredson, Earl Duvall | Newspaper strip | 5 | Daily strips (US) | 79 |
| Topolino e l'unghia di Kalì | 1958 | Romano Scarpa | Story | 50 | Italy | 78 |
| Topokolossal | 1997 | Silvia Ziche | Story | 200 | Italy | 76 |
| Goofy's Prize Fight | 1946 | Don Gunn | Story | 23 | Western | 76 |
| The Brave Little Tailor | 1952 | Merrill De Maris, Dick Hall | Story | 16 | Western | 76 |
| MM | 1978 | | Illustration | 1 | Western | 76 |
| Arrête ton char, Mickus ! | 1962 | Pierre Fallot, Pierre Nicolas | Story | 12 | France | 75 |
| Tutto questo accadde domani | 2018 | Casty | Story | 88 | Italy | 75 |
| Message in a Nutshell | 1972 | Paul Murry | Story | 24 | Western | 75 |
| Robin Mickey and the Sheriff of Blottingham | 1965 | Paul Murry | Story | 18 | Western | 73 |
| Topolino e il mondo che verrà | 2008 | Casty | Story | 72 | Italy | 72 |
| Dracula di Bram Topker | 2012 | Bruno Enna, Fabio Celoni | Story | 72 | Italy | 72 |
| Topolino e il Torneo dell'Argaar | 1983 | Massimo De Vita | Story | 80 | Italy | 71 |
| Paperino e l'incombenza natalizia | 2010 | Tito Faraci, Giampaolo Soldati | Story | 40 | Italy | 70 |
| Friends from Duckburg/Mouseton | 2018 | | Illustration | 2 | Disney Publishing Worldwide (global) | 70 |
| Topolino e la dimensione Delta | 1959 | Romano Scarpa | Story | 72 | Italy | 69 |
| Dr Mouse M.D. | 2009 | Fausto Vitaliano, Alessandro Perina | Story | 69 | Italy | 69 |
| This Is Your Life, Donald Duck | 1960 | Vic Lockman, Tony Strobl | Story | 31.9 | Western | 68 |
| Pluto's Rival | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 10 | Daily strips (US) | 68 |
| Caws and Effect | 1953 | Don Christensen, Paul Murry | Story | 6 | Western | 67 |
| The Old Pirate's Mansion | 1972 | Paul Murry | Story | 24 | Western | 66 |
| The War Orphans | 1944 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 30 | Daily strips (US) | 66 |
| Untitled newspaper strip | 1949 | Bill Walsh, Manuel Gonzales | Newspaper strip | 1 | Sunday pages (US) | 66 |
| I.Q. Switcheroo | 1958 | Paul Murry | Story | 4 | Western | 65 |
| Operation Ark | 1960 | Carl Fallberg, Tony Strobl | Story | 14 | Western | 65 |
| The Mysterious Knight Rider | 1968 | Paul Murry | Story | 21 | Western | 65 |
| The Moose Monster Mystery | 1969 | Paul Murry | Story | 21 | Western | 65 |
| Paperin De La Scalogna e il re dell'arena | 1970 | Guido Martina, Giovan Battista Carpi | Story | 29 | Italy | 64 |
| Topolino e Minni in "Casablanca" | 1987 | Giorgio Cavazzano | Story | 52 | Italy | 64 |
| Topolino e il mistero della voce spezzata | 1991 | Silvano Mezzavilla, Giorgio Cavazzano | Story | 52 | Italy | 64 |
| Topolino e la rapina del millennio | 2008 | Silvia Ziche | Story | 140 | Italy | 64 |
| Il nuovo mondo | 2009 | Stefano Ambrosio, Lorenzo Pastrovicchio | Story | 153 | Italy | 64 |
| An Education for Thursday | 1960 | Merrill De Maris, Paul Murry | Story | 40 | Western | 64 |
| Flight of the Dragon | 1973 | Alpine Harper, Paul Murry | Story | 24 | Western | 64 |
| Home Movies | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 64 |
| Chi ha rubato Topolino 2000? | 1994 | Carlo Panaro, Romano Scarpa | Story | 99 | Italy | 63 |
| L'isola dei misteri | 2020 | Francesco Artibani, Lorenzo Pastrovicchio | Story | 74 | Italy | 63 |
| Boulimie... ckey | 1962 | Pierre Fallot, Pierre Nicolas | Story | 8 | France | 62 |
| Topolino presenta: Cristoforo Colombo | 1983 | Guido Martina, Giovan Battista Carpi | Story | 89 | Italy | 62 |
| Darkenblot | 2012 | Casty, Lorenzo Pastrovicchio | Story | 92 | Italy | 62 |
| The Big Christmas Tree Mystery | 1955 | Carl Fallberg, Paul Murry | Story | 17 | Western | 62 |
| The Cure for Hiccups | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 62 |
| With Uncle Mukluk | 1959 | Carl Fallberg, Paul Murry | Story | 6 | Western | 61 |
| Mickey's Menagerie | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 61 |
| The Crystal Ball Quest | 1957 | Carl Fallberg, Paul Murry | Story | 15 | Western | 60 |
| Eviction | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 60 |
| The Mystery Next Door | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 18 | Daily strips (US) | 59 |
| Untitled newspaper strip | 1932 | Floyd Gottfredson | Newspaper strip | 1 | Sunday pages (US) | 59 |
| 60 anni insieme con Topolino | 1993 | Luca Boschi, Andrea Ferraris | Story | 88 | Italy | 58 |
| A 1934 Belchfire Runabout | 1984 | Carl Barks | Lithograph | 1 | Miscellaneous | 57 |
| A Mickey Mystery | 2013 | Byron Erickson, Cèsar Ferioli Pelaez | Story | 22 | Denmark | 57 |
| Topolino e la bella addormentata nel cosmo | 1993 | Fabio Michelini, Massimo De Vita | Story | 66 | Italy | 57 |
| Untitled newspaper strip | 1932 | Floyd Gottfredson | Newspaper strip | 1 | Sunday pages (US) | 57 |