| (Il segreto del totem decapitato) | 1973 | Guido Martina, Giovan Battista Carpi | Story | 241 | Italy | 224 |
| Dry Gulch Goofy | 1951 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 78 | Daily strips (US) | 220 |
| L'età oscura | 2007 | Stefano Ambrosio, Alessandro Perina | Story | 288 | Italy | 217 |
| Pflip's Strange Power | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 60 | Daily strips (US) | 215 |
| The Mystery at Hidden River | 1950 | Merrill De Maris, Bill Wright | Story | 46.8 | Western | 213 |
| The Magic Shoe | 1953 | Bill Walsh, Bill Wright | Newspaper strip | 111 | Daily strips (US) | 213 |
| Untitled illustration | 1999 | Lorenzo Pastrovicchio | Illustration | 2 | Italy | 211 |
| The Black Crow Mystery | 1942 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 84 | Daily strips (US) | 202 |
| An Education for Eega Beeva | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 66 | Daily strips (US) | 201 |
| Mickey's Dangerous Double | 1953 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 96 | Daily strips (US) | 201 |
| Li'l Davy | 1955 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 86 | Daily strips (US) | 196 |
| The Lair of Wolf Barker | 1933 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 21 | Sunday pages (US) | 194 |
| Rumplewatt the Giant | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 8 | Sunday pages (US) | 194 |
| The 'Lectro Box | 1943 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 90 | Daily strips (US) | 192 |
| Love Trouble | 1941 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 72 | Daily strips (US) | 191 |
| The Ghost of Black Brian | 1951 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 102 | Daily strips (US) | 184 |
| Clarabelle's Boarding House | 1931 | Floyd Gottfredson | Newspaper strip | 35 | Daily strips (US) | 181 |
| The Midas Ring | 1952 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 76 | Daily strips (US) | 181 |
| High Society | 1931 | Floyd Gottfredson | Newspaper strip | 26 | Daily strips (US) | 173 |
| Mighty Whale Hunter | 1950 | Merrill De Maris, Bill Wright | Story | 66 | Western | 167 |
| Helpless Helpers | 1936 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 4 | Sunday pages (US) | 162 |
| The House of Mystery | 1944 | Bill Walsh, Dick Moores | Newspaper strip | 66 | Daily strips (US) | 159 |
| ...a Topolinia | 2015 | Silvia Ziche | Story | 1 | Italy | 158 |
| Supersalesman | 1941 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 78 | Daily strips (US) | 154 |
| Fireman Mickey | 1931 | Floyd Gottfredson | Newspaper strip | 19 | Daily strips (US) | 144 |
| The Mystery of the Double-Cross Ranch | 1950 | Paul Murry | Story | 32 | Western | 143 |
| Mickey Makes a Killing | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 36 | Daily strips (US) | 141 |
| Tanglefoot Pulls His Weight | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 5 | Sunday pages (US) | 139 |
| The Bar None Ranch | 1959 | Merrill De Maris, Paul Murry | Story | 40 | Western | 138 |
| Foray to Mt. Fishflake | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 7 | Sunday pages (US) | 138 |
| Outwits the Phantom Blot | 1949 | Merrill De Maris, Bill Wright | Story | 48 | Western | 136 |
| La storia di Marco Polo detta Il Milione | 1982 | Guido Martina, Romano Scarpa | Story | 126 | Italy | 131 |
| L'inferno di Topolino | 1949 | Guido Martina, Angelo Bioletto | Story | 69 | Italy | 127 |
| Le sette meraviglie dei paperi | 1990 | Fabio Michelini, Giuseppe Dalla Santa | Story | 227 | Italy | 127 |
| The House of the Seven Haunts | 1949 | Ted Osborne, Dick Moores | Story | 46 | Western | 127 |
| The Santa Claus Bandit | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 31 | Daily strips (US) | 127 |
| Pluto in Love Trouble | 1955 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 30 | Daily strips (US) | 127 |
| The Riddle of the Red Hat | 1945 | Carl Barks | Story | 11 | Western | 122 |
| Service with a Smile | 1938 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 5 | Sunday pages (US) | 120 |
| Mickey's Mini-plane | 1946 | Bill Walsh, Bill Wright | Newspaper strip | 18 | Daily strips (US) | 117 |
| Topolino e la spada di ghiaccio | 1982 | Massimo De Vita | Story | 103 | Italy | 115 |
| The Sorcerer of Donnybrook Castle | 1969 | Alpine Harper, Paul Murry | Story | 24 | Western | 113 |
| Mickey's Rival | 1936 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 4 | Sunday pages (US) | 113 |
| Índice | 1979 | Marco Rota | Illustration | 1 | Italy | 112 |
| The Picnic | 1931 | Floyd Gottfredson | Newspaper strip | 6 | Daily strips (US) | 106 |
| Mickey's Helicopter | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 105 |
| Aunt Marissa | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 104 |
| Molti personaggi in: la scatola misteriosa nel luogo misteriosissimo | 2017 | Sio, Nicolino Picone | Story | 52 | Italy | 101 |
| The Mysterious Crystal Ball | 1954 | Paul Murry | Story | 24 | Western | 101 |
| The Treasure of Oomba Loomba | 1966 | Alpine Harper, Paul Murry | Story | 40 | Western | 101 |
| The Sign of the Scorpion | 1970 | Paul Murry | Story | 24 | Western | 101 |
| The Pirates of Port Placid | 1971 | Carl Fallberg, Paul Murry | Story | 24 | Western | 100 |
| The Thief of Zanzipar | 1965 | Bob Ogle, Paul Murry | Story | 16 | Western | 98 |
| Monkey Business | 1950 | Tony Strobl | Story | 23 | Western | 97 |
| Adventures With Robin Hood | 1955 | Ted Osborne, Jack Bradbury | Story | 40 | Western | 96 |
| The Kumquat Question | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 21 | Daily strips (US) | 96 |
| The Thunderbolt Machine | 1954 | Tony Strobl | Story | 22 | Western | 94 |
| Feat of Fancy | 1950 | Tony Strobl | Story | 20 | Western | 94 |
| The Viking Raiders | 1968 | Carl Fallberg, Paul Murry | Story | 21 | Western | 93 |
| Chief Bigfoot and the Ghost Warriors | 1970 | Alpine Harper, Paul Murry | Story | 24 | Western | 91 |