| Hoosat from Another Planet | 1952 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 128 | Daily strips (US) | 235 |
| The Mystery at Hidden River | 1941 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 90 | Daily strips (US) | 234 |
| (Il segreto del totem decapitato) | 1973 | Guido Martina, Giovan Battista Carpi | Story | 241 | Italy | 224 |
| Dry Gulch Goofy | 1951 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 78 | Daily strips (US) | 220 |
| Mousepotamia | 1950 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 72 | Daily strips (US) | 219 |
| L'età oscura | 2007 | Stefano Ambrosio, Alessandro Perina | Story | 288 | Italy | 217 |
| Uncle Wombat's Tock Tock Time Machine | 1951 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 80 | Daily strips (US) | 216 |
| Pflip's Strange Power | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 60 | Daily strips (US) | 215 |
| The Mystery at Hidden River | 1950 | Merrill De Maris, Bill Wright | Story | 46.8 | Western | 213 |
| The Magic Shoe | 1953 | Bill Walsh, Bill Wright | Newspaper strip | 111 | Daily strips (US) | 213 |
| Untitled illustration | 1999 | Lorenzo Pastrovicchio | Illustration | 2 | Italy | 211 |
| Land Beneath the Sea | 1950 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 78 | Daily strips (US) | 211 |
| Mickey Mouse Vs. Kat Nipp | 1931 | Floyd Gottfredson, Earl Duvall | Newspaper strip | 33 | Daily strips (US) | 205 |
| The Black Crow Mystery | 1942 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 84 | Daily strips (US) | 202 |
| An Education for Eega Beeva | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 66 | Daily strips (US) | 201 |
| Itching Gulch | 1949 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 66 | Daily strips (US) | 201 |
| Tzig-tzag Fever | 1951 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 72 | Daily strips (US) | 201 |
| Mickey's Dangerous Double | 1953 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 96 | Daily strips (US) | 201 |
| Li'l Davy | 1955 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 86 | Daily strips (US) | 196 |
| The Lair of Wolf Barker | 1933 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 21 | Sunday pages (US) | 194 |
| Rumplewatt the Giant | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 8 | Sunday pages (US) | 194 |
| The 'Lectro Box | 1943 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 90 | Daily strips (US) | 192 |
| Love Trouble | 1941 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 72 | Daily strips (US) | 191 |
| Circus Roustabout | 1931 | Floyd Gottfredson | Newspaper strip | 33 | Daily strips (US) | 188 |
| The Ghost of Black Brian | 1951 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 102 | Daily strips (US) | 184 |
| Clarabelle's Boarding House | 1931 | Floyd Gottfredson | Newspaper strip | 35 | Daily strips (US) | 181 |
| The Midas Ring | 1952 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 76 | Daily strips (US) | 181 |
| Ultraheroes | 2008 | Alessandro Ferrari, Antonello Dalena | Story | 240 | Italy | 179 |
| I bis-bis di Pippo | 2006 | Alessandro Sisti, Andrea Ferraris | Story | 221 | Italy | 178 |
| Mickey and the Beanstalk | 1947 | Harvey Eisenberg | Story | 39 | Western | 177 |
| MM On a Secret Mission | 1943 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 84 | Daily strips (US) | 174 |
| High Society | 1931 | Floyd Gottfredson | Newspaper strip | 26 | Daily strips (US) | 173 |
| Ridin' the Rails | 1955 | Carl Fallberg, Paul Murry | Story | 24 | Western | 169 |
| Mighty Whale Hunter | 1950 | Merrill De Maris, Bill Wright | Story | 66 | Western | 167 |
| The Case of the Vanishing Coats | 1935 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 6 | Sunday pages (US) | 166 |
| Goofy's Inheritance | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 165 |
| Battle the Giant Ants | 1950 | Bill Wright | Story | 25 | Western | 164 |
| Helpless Helpers | 1936 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 4 | Sunday pages (US) | 162 |
| The Case of the Vanishing Bandit | 1954 | Carl Fallberg, Paul Murry | Story | 26 | Western | 160 |
| Untitled newspaper strip | 1940 | Merrill De Maris, Manuel Gonzales | Newspaper strip | 18 | Sunday pages (US) | 160 |
| Unhappy Campers | 1939 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 31 | Daily strips (US) | 159 |
| The House of Mystery | 1944 | Bill Walsh, Dick Moores | Newspaper strip | 66 | Daily strips (US) | 159 |
| Mickey's Pet Shop | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 157 |
| Supersalesman | 1941 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 78 | Daily strips (US) | 154 |
| Ohé ! Ivanhoé ! | 1962 | Pierre Fallot, Pierre Nicolas | Story | 26 | France | 150 |
| The Ventriloquist | 1936 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 5 | Sunday pages (US) | 150 |
| Fireman Mickey | 1931 | Floyd Gottfredson | Newspaper strip | 19 | Daily strips (US) | 144 |
| The Mystery of the Double-Cross Ranch | 1950 | Paul Murry | Story | 32 | Western | 143 |
| The Ghost of Man-Eater Mountain | 1951 | Don Christensen, Bill Wright | Story | 42 | Western | 142 |
| Mickey Makes a Killing | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 36 | Daily strips (US) | 141 |
| The Submarine Pirates | 1947 | Harvey Eisenberg | Story | 22 | Western | 139 |
| Tanglefoot Pulls His Weight | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 5 | Sunday pages (US) | 139 |
| The Magic Rope | 1954 | Paul Murry | Story | 24 | Western | 138 |
| The Bar None Ranch | 1959 | Merrill De Maris, Paul Murry | Story | 40 | Western | 138 |
| Foray to Mt. Fishflake | 1934 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 7 | Sunday pages (US) | 138 |
| Outwits the Phantom Blot | 1949 | Merrill De Maris, Bill Wright | Story | 48 | Western | 136 |
| Les mystères de la Tour Eiffel | 1950 | André-Paul Duchâteau, Tenas | Story | 34 | Belgium | 136 |
| The Return of the Phantom Blot | 1964 | Paul Murry | Story | 31.8 | Western | 135 |
| ...a Topolinia | 2015 | Silvia Ziche | Story | 1 | Italy | 132 |
| The Mystery of the Robot Army! | 1951 | Stan Walsh | Story | 45 | Western | 132 |