| Dan, the Dogcatcher | 1932 | Floyd Gottfredson | Newspaper strip | 5 | Sunday pages (US) | 132 |
| La storia di Marco Polo detta Il Milione | 1982 | Guido Martina, Romano Scarpa | Story | 126 | Italy | 131 |
| L'inferno di Topolino | 1949 | Guido Martina, Angelo Bioletto | Story | 69 | Italy | 127 |
| Le sette meraviglie dei paperi | 1990 | Fabio Michelini, Giuseppe Dalla Santa | Story | 227 | Italy | 127 |
| The House of the Seven Haunts | 1949 | Ted Osborne, Dick Moores | Story | 46 | Western | 127 |
| The Pirates of Tabasco Bay | 1956 | Carl Fallberg, Paul Murry | Story | 23.8 | Western | 127 |
| The Santa Claus Bandit | 1948 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 31 | Daily strips (US) | 127 |
| Pluto in Love Trouble | 1955 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 30 | Daily strips (US) | 127 |
| The Phantom Fires | 1957 | Carl Fallberg, Paul Murry | Story | 24 | Western | 126 |
| The Sunken City | 1957 | Carl Fallberg, Paul Murry | Story | 24 | Western | 125 |
| The Talking Dog | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 125 |
| The Wonderful Whizzix | 1952 | Dick Moores | Story | 24 | Western | 124 |
| The Riddle of the Red Hat | 1945 | Carl Barks | Story | 11 | Western | 122 |
| The Vanishing Railroad | 1956 | Carl Fallberg, Paul Murry | Story | 23.5 | Western | 122 |
| The King Of The Copper Hill | 1993 | Don Rosa | Story | 15 | Denmark | 120 |
| Service with a Smile | 1938 | Merrill De Maris, Floyd Gottfredson | Newspaper strip | 5 | Sunday pages (US) | 120 |
| Goofy's Mechanical Wizard | 1952 | Dick Moores | Story | 20 | Western | 119 |
| The Great Stamp Hunt | 1956 | Carl Fallberg, Paul Murry | Story | 23.5 | Western | 119 |
| The Secret of the Whirlpool | 1953 | Carl Fallberg, Dick Moores | Story | 24 | Western | 118 |
| Mickey's Mini-plane | 1946 | Bill Walsh, Bill Wright | Newspaper strip | 18 | Daily strips (US) | 117 |
| Topolino e la spada di ghiaccio | 1982 | Massimo De Vita | Story | 103 | Italy | 115 |
| Mickey Mouse's Magic Machine | 1947 | Dick Moores | Story | 25 | Western | 115 |
| The Lost Legion | 1954 | Paul Murry | Story | 26 | Western | 115 |
| The Bush Pilot's Peril | 1958 | Carl Fallberg, Paul Murry | Story | 17 | Western | 114 |
| The Monster of Sawtooth Mountain | 1959 | Carl Fallberg, Paul Murry | Story | 25 | Western | 114 |
| Alaskan Adventure | 1959 | Carl Fallberg, Paul Murry | Story | 24 | Western | 114 |
| The Sorcerer of Donnybrook Castle | 1969 | Alpine Harper, Paul Murry | Story | 24 | Western | 113 |
| Mickey's Rival | 1936 | Ted Osborne, Floyd Gottfredson | Newspaper strip | 4 | Sunday pages (US) | 113 |
| Índice | 1979 | Marco Rota | Illustration | 1 | Italy | 112 |
| Pineapple Poachers | 1960 | Carl Fallberg, Paul Murry | Story | 24 | Western | 112 |
| Robin des Pois | 1960 | Pierre Fallot, Pierre Nicolas | Story | 18 | France | 111 |
| Untitled cover | 1949 | Ambrogio Vergani | Cover | 1 | Italy | 111 |
| The Treasure of El Dorado | 1962 | Carl Fallberg, Paul Murry | Story | 24 | Western | 111 |
| The Timber Treasure Trail | 1958 | Carl Fallberg, Paul Murry | Story | 18 | Western | 109 |
| The Idol of Moaning Island | 1958 | Carl Fallberg, Paul Murry | Story | 24 | Western | 108 |
| The Mystery at Painted Valley | 1951 | Bill Weaver | Story | 24 | Western | 107 |
| The Giant Pearls of Agoo Island | 1956 | Charles Beaumont, Paul Murry | Story | 19 | Western | 106 |
| The Secret of the Swamp | 1959 | Carl Fallberg, Paul Murry | Story | 20 | Western | 106 |
| The Picnic | 1931 | Floyd Gottfredson | Newspaper strip | 6 | Daily strips (US) | 106 |
| Mickey's Helicopter | 1947 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 105 |
| The Ruby Eye of Homar-Guy-Am | 1951 | Don Christensen, Paul Murry | Story | 16 | Western | 104 |
| The Castaways of Whale Bay | 1958 | Carl Fallberg, Paul Murry | Story | 24 | Western | 104 |
| Aunt Marissa | 1946 | Bill Walsh, Floyd Gottfredson | Newspaper strip | 12 | Daily strips (US) | 104 |
| The Marvelous Magnet | 1955 | Carl Fallberg, Paul Murry | Story | 24 | Western | 103 |
| The Mystery Monster from Smoggy Bog | 1972 | Paul Murry | Story | 24 | Western | 103 |
| The Duck Who Never Was | 1994 | Don Rosa | Story | 16 | Denmark | 101 |
| Molti personaggi in: la scatola misteriosa nel luogo misteriosissimo | 2017 | Sio, Nicolino Picone | Story | 52 | Italy | 101 |
| The Mysterious Crystal Ball | 1954 | Paul Murry | Story | 24 | Western | 101 |
| The Case of the Hungry Ghost | 1956 | Carl Fallberg, Paul Murry | Story | 23.8 | Western | 101 |
| The Treasure of Oomba Loomba | 1966 | Alpine Harper, Paul Murry | Story | 40 | Western | 101 |
| The Sign of the Scorpion | 1970 | Paul Murry | Story | 24 | Western | 101 |
| The Last Resort | 1953 | Carl Fallberg, Paul Murry | Story | 24 | Western | 100 |
| The Pirates of Port Placid | 1971 | Carl Fallberg, Paul Murry | Story | 24 | Western | 100 |
| Κρυπτόλεξο | 2007 | | Game or puzzle | 1 | Non-Disney and/or non-comics | 99 |
| The Case of the Dazzling Hoo-Doo | 1968 | Carl Fallberg, Paul Murry | Story | 24 | Western | 99 |
| The Thief of Zanzipar | 1965 | Bob Ogle, Paul Murry | Story | 16 | Western | 98 |
| The Great Giveaway Mystery | 1961 | Carl Fallberg, Paul Murry | Story | 24 | Western | 98 |
| Journey to No-No Land | 1970 | Alpine Harper, Paul Murry | Story | 24 | Western | 98 |
| Monkey Business | 1950 | Tony Strobl | Story | 23 | Western | 97 |
| The Fantastic Fog | 1959 | Carl Fallberg, Paul Murry | Story | 24 | Western | 97 |